A flavoprotein containing iron. Cytochrome c may act as receptor. The enzyme reversibly catalyses the oxidation of NADH to NAD and reduced acceptor.
An inherited deficiency of this complex results in overwhelming acidosis.
Synonym: cytochrome c reductase.
Chemical name: NADH:(acceptor) oxidoreductase
Registry number: EC 1.6.99.3
(12 Dec 1998)