S-adenosyl-l-methionine

S-(5'-deoxy-5'-adenosyl)-l-methionine;condensation product of adenosine and l-methionine involving replacement of the -OPO3H2 of adenylic acid by -S+ (CH3)CH2CH2CH(NH3+)CO 2 of methionine; a sulfonium compound bearing a methyl group that is transferred in transmethylation reactions.

See: methionine adenosyltransferase.

Synonym: active methionine.

Acronym: SAM

(05 Mar 2000)


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