Receptors for SNAPs. The neuronal receptor for vesicle SNAPs, v SNARE, is synaptobrevin, also called VAMP 2. The target (t SNARE) associated with the plasma membrane of the axonal terminal is syntaxin. The SNAP SNARE complex is apparently responsible for regulating vesicle targeting: neurotoxins such as tetanus toxin and botulinum toxin selectively cleave SNAREs or SNAPs.
See: cellubrevin.
(18 Nov 1997)