A test that measures the respective quantities of B lymphocytes and T lymphocytes. This test is often performed in the analysis of an immune deficiency disorder. Normal values include: 68 to 75% of total lymphocytes are T lymphocytes and 10 to 20% are B lymphocytes.
Increased T-cell counts can indicate infectious mononucleosis, acute lymphocytic leukaemia or multiple myeloma.
Increased B lymphocytes can indicate chronic lymphocytic leukaemia, multiple myeloma, Waldenstrom's macroglobulinaemia or Di George syndrome. Decreased T-cells may indicate congenital T-cell deficiency, Wiskott-Aldrich syndrome or AIDS. Decreased B-cells may indicate acute lymphocytic leukaemia or a congenital immunoglobulin deficiency disorder.
(27 Sep 1997)